To the possibility of detecting the "coronary theft" syndrome in small laboratory animals

The purpose of the study. There are investigation possibility using laser Doppler flowmetry method to assess blood microcirculation and analyze mechanisms its regulation in conditionally intact ischemic myocardium small laboratory animals (rats) identify "coronary theft" syndrome. Materials methods. experiments were carried out on white mongrel anesthetized (urethane 1300 mg/kg /b) male rats weighing 200-250 g. 28 days after reproduction an experimental myocardial infarction open chest artificial lung ventilation, level was assessed areas by flowmetry. Using spectral wavelet analysis, amplitudes oscillations normalized total perfusion associated with various determined. Results. It found that is significantly lower zone compared one (17.3±2.8 30.3±1.3 per. units, respectively, p = 0.006, n 8). Spectral analysis showed injury zone, comparison myocardium, general increase for all regulatory mechanisms. Conclusion. can be used intensity myocardium. this makes it possible syndrome animals.